Schmoes are people who are not very important or special.
Calling someone a schmo is not very nice.
Examples:
The boss only talks to the important people, not the schmoes.
The schmoes have to wait in line.
He is just a schmo, not a big deal.
The schmoes always have to do the boring work.
The schmoes never get to go to the fun parties.
I don't want to be a schmo, I want to be important.