Shinola is a brand of shoe polish. It is also used in the phrase 'can't tell shit from Shinola' to mean someone is very confused or doesn't know anything.
Shinola is a brand name, and the phrase using 'Shinola' is a little rude or funny.
Examples:
I used Shinola to polish my shoes.
He doesn't know shit from Shinola.
Do you have any Shinola for my shoes?
I can't tell shit from Shinola when it comes to fixing cars.
She thinks I can't tell shit from Shinola, but I know a lot about computers.
I can't tell shit from Shinola when it comes to cooking.